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PROTO-ONCOGENE PROTEINS C-MAF
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins c-maf
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas c-maf
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas c-maf
Synonyms
English
:
c-maf Protein
maf Proto-Oncogene Protein
Tree Number:
D12.776.260.108.500.061.750
D12.776.624.664.700.184
D12.776.930.127.500.061.750
Definition
English
:
Maf proto-oncogene protein is the major cellular homolog of the V-MAF ONCOGENE PROTEIN. It was the first of the mammalian
MAF TRANSCRIPTION FACTORS
identified, and it is induced in activated
T-LYMPHOCYTES
and regulates GENETIC TRANSCRIPTION of
INTERLEUKIN-4
. c-maf is frequently translocated to an immunoglobulin locus in
MULTIPLE MYELOMA.
History Note
English
:
2006(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50968
Unique Identifier:
D051257
Occurrence in VHL
:
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